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Practical, distro-agnostic guide to stand up reliable, secure AI-ready Linux hosts. Covers baseline setup on Ubuntu/Debian, Fedora/RHEL, and openSUSE; reproducible Python venvs; optional NVIDIA GPU drivers and container toolkit; rootless containers with Podman; operating tips with systemd, cgroups, htop/nvtop, and firewalls; plus a FastAPI model served as a systemd service and real-world automation advice.